2D-functionalized Glass Slides

For cost-sensitive applications PolyAn microarray products include a range of 2D (2-dimensional)-reactive glass slides that are manufactured from high quality glass with an ultra-flat surface and low inherent fluorescence. The glass is coated with a thin silane layer that will covalently bind most types of bio-molecules. The defect-free surface features uniform silane layers that provide a high covalent coupling efficiency together with a very low background. The slides are easy to use, and are fully compatible with all commercially available arraying and scanning instruments. The glass slides are 25.0 x 75.6 mm and are available as 5- or 25-packs.

3D-functionalized Glass Slides

PolyAn’s functionalized slides for microarrays are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the slide. The glass slides are 25.0 x 75.6 mm and are available as 5- or 25-packs.

Packaging: The slides are packaged in inert atmospheric boxes, with a capacity of 25 or 5 slides per box.

Storage: PolyAn’s slides are characterized by a long shelf-life when stored dry, at 4-8°C and protected from sunlight. All slides are packaged in boxes under Argon atmosphere to avoid contamination with particles. The Argon atmosphere also minimizes degradation of the reactive surface through contact with air or humidity.

Functionalized Polymer Slides

Especially for diagnostic applications, PolyAn microarray products include a broad range of functionalized microarray polymer slides. For reasons of reliability and bio-safety, patient-centric biomarker testing is always performed in single-use cartridges with a one-step process (sample in – result out). These cartridges should be disposable after use, so the materials of the cartridge should be non-hazardous and recyclable.

PolyAn’s COP Polymer Slides are comprised of a low auto fluorescence plastic. The material is highly robust against breakage making it the material of choice when working with hazardous materials. It is suitable for injection molding and hot embossing processes.

The slides are produced with standard dimensions of 25 x 75 x 1 mm.

2D-Functionalized Coverslips

For high-resolution microscopic imaging or scanning applications PolyAn offers functionalized coverslips. All of PolyAn’s standard functional coatings can also be applied to coverslip glass.

All coverslips have the standard dimension of 25 x 60mm. Type #1.5 is used as a standard thickness. All coverslips are packed in boxes of 5. Other functionalities, thicknesses and sizes are available upon request. PolyAn also offers functionalised substrates that are coated with gold or other noble metals as well as waveguide materials.

3D-Functionalized Coverslips

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3D-Functionalized Polymer Films

Functionalized Cyclo Olefin Polymer (COP) films with low autofluorescence that can be easily cut into suitable formats post printing. COP is characterized by a low autofluorescence. The finished film-chip can be easily integrated into cartridges or microfluidic devices.

The sheets are available in slide format (75 mm x 25 mm) as well as larger sheets (75 mm x 110 mm). They are 188 micron thick, and sold as 5 sheets per box. Customized pre-scored sheets are available upon request.

Please download the Application Note “Assembling of spotted, pre-cut COP sensor foil with DNA-microarray on a microfluidic hybridization cartridge” here.

Functionalized Microtiter Plates.

In order to take advantage of the existing liquid handling and automation solutions for 96-well and 384-well SBS formats, PolyAn microarray products include a full range of functionalized multiwell products which are equipped with the same reactive surfaces as our glass and plastic slides. Standard polystyrene 96-well and 384-well plates in different designs which are equipped with PolyAn’s reactive matrices for covalent coupling of biomolecules.

Key features:

• Compatible with all liquid handling systems for ELISA
• Covalent binding of nucleophiles to the plate surface without complex coupling chemistry
• Integrated antifouling matrix reduces unspecific binding
• No cross-contamination between wells possible
• Most cost-efficient solution

3D-Functionalized 96-well solid plates

Functionalized plates for microarrays include black polystyrene uClear (from Greiner Bio-One).

3D-Functionalized 96-well strip plates

Functionalized plates for microarrays also include strip plates that consists of 12 x 8-well strips, with flat bottom wells. They offer the best flexibility when usage doesn’t always involve using a full plate.

These plates are either white or transparent polystyrene (from Greiner Bio-One).

3D-Functionalized 96-well 2-part plates

Multipart plates consists of a flat bottom and 96-well frame. PolyAn’s multipart plates are comprised of a functionalized glass plate (75 x 110 mm, 1mm thickness) which is combined with the ProPlate superstructure after the printing process.

Products listed include both the glass bottom and the plate frame (round or square wells).

3D-Functionalized 384-well 2-part plates

Multipart plates consists of a flat bottom and 384-well frame. PolyAn’s multipart plates are comprised of a functionalized glass plate (75 x 110 mm, 1mm thickness) which is combined with the ProPlate superstructure after the printing process.

Products listed include both the glass bottom and the plate frame with square wells.